getSImputed: Get imputed data

In cz-ye/DECENT: Differential Expression with Capture Efficiency adjustmeNT

Get imputed data

Description

Get single imputed data by sampling from the posterior distribution of the complete data given the observed data and LRT estimates.

Usage

getSImputed(data.obs, par.est, sf, CE, XW, tau, parallel = T)

Arguments

data.obs	Observed count matrix for endogeneous genes, rows represent genes, columns represent cells
par.est	LRT/EM estimates, using par.DE by default
sf	A vector containing size factors for all cells
CE	A vector containing capture efficiencies for all cells
XW	A matrix containing information for X (cell-type) and W (other covariates)
tau	cell-specific estimates (intcp,slope) that link Beta-Binomial dispersion parameter to the mean expression.
parallel	If TRUE, run in parallel
M	number of imputed values to be generated.

Value

A matrix containing the single imputed data.

cz-ye/DECENT documentation built on Jan. 25, 2023, 5:57 a.m.