databio/RPIM: Assess epigenetic heterogeneity with proportion of intermediate methylation
Provides a score called PIM that measures the epigenetic heterogeneity in a bisulfite sequencing sample. Under the assumption that a homogeneous sample will have mostly CpGs with either 100% or 0% DNA methylation, it follows that the proportion of sites that differ from these two extremes can be used as a measure of sample heterogeneity.
Getting started
Browse package contents
Package details |
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| Bioconductor views | Bayesian Coverage DNAMethylation Epigenetics MethylSeq Sequencing |
| Maintainer | VP Nagraj <vpnagraj@virginia.edu> |
| License | GPL-3 |
| Version | 0.1.0 |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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