Provides a score called PIM that measures the epigenetic heterogeneity in a bisulfite sequencing sample. Under the assumption that a homogeneous sample will have mostly CpGs with either 100% or 0% DNA methylation, it follows that the proportion of sites that differ from these two extremes can be used as a measure of sample heterogeneity.
Package details 


Bioconductor views  Bayesian Coverage DNAMethylation Epigenetics MethylSeq Sequencing 
Maintainer  VP Nagraj <[email protected]> 
License  GPL3 
Version  0.1.0 
Package repository  View on GitHub 
Installation 
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