Provides a score called PIM that measures the epigenetic heterogeneity in a bisulfite sequencing sample. Under the assumption that a homogeneous sample will have mostly CpGs with either 100% or 0% DNA methylation, it follows that the proportion of sites that differ from these two extremes can be used as a measure of sample heterogeneity.
|Bioconductor views||Bayesian Coverage DNAMethylation Epigenetics MethylSeq Sequencing|
|Maintainer||VP Nagraj <[email protected]>|
|Package repository||View on GitHub|
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