Circ.filter: Circ.filter

Description Usage Arguments

Description

Filter circRNA candidates based on expression level. User specify how many samples (filter.sample) need to have above which minimum number (filter.count) of read count support. In addition, circRNA need to account for which percentage (percentage) of the total transcripts in at least one group.

Usage

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Circ.filter(circ = circ, linear = linear, Nreplicates = 6,
  filter.sample = 4, filter.count = 5, percentage = 1,
  circle_description = c(1:3))

Arguments

circ

CircRNACount file. A file of circRNA read count table. First three columns are circRNA coordinates, and followed by columns for circRNA read counts, each sample per column.

linear

LinearCount file. A file of circRNA host gene expression count table. Same configuration as CircRNACount file.

Nreplicates

Number of replicates in your data. Expect each group have the same number of replicates.

filter.sample

The minimum number of samples need to have above filter.count number of circRNA supporting reads.

filter.count

The minimum read count used for filtering.

percentage

The minimum percentage of circRNAs account for the total transcripts in at leat one group.

circle_description

Column indices which do not carry circle/linear read counts.


dieterich-lab/CircTest documentation built on May 15, 2019, 8:29 a.m.