rnaiscreen: A pan-viral perturbation dataset

Description Usage Format References Examples

Description

Example PerturbationData object consisting of several integrated viral RNAi screens.

Usage

1

Format

A PerturbationData object containing a tibble with 16 columns, each describing a feature.

References

de Wilde, Adriaan H, et al. (2015), A kinome-wide small interfering RNA screen identifies proviral and antiviral host factors in severe acute respiratory syndrome coronavirus replication, including double-stranded RNA-activated protein kinase and early secretory pathway proteins.
Journal of Virology

Reiss, Simon, et al. (2011), Recruitment and activation of a lipid kinase by hepatitis C virus NS5A is essential for integrity of the membranous replication compartment.
Cell Host & Microbe

Poenisch, Marion, et al. (2015), Identification of HNRNPK as Regulator of Hepatitis C Virus Particle Production.
PLoS Pathogens

Cortese, Mirko, et al. (2019), Reciprocal Effects of Fibroblast Growth Factor Receptor Signaling on Dengue Virus Replication and Virion Production.
Cell Reports

Examples

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 data(rnaiscreen)
 fit <- hm(rnaiscreen)
 pls <- plot(fit)
 pls[[1]]

dirmeier/knockout documentation built on Feb. 15, 2020, 9:11 p.m.