calcPlateStats: Calculate plate statistics

In dmattek/hcs-package:

Description

Calculates NPI (normalized percentage inhibition) and z-score for a plate.

Usage

calcPlateStats(in.dt, in.col.meas, in.col.well, in.wells.neg, in.wells.pos,
  in.wells.untr = NULL)

Arguments

in.dt	Input data table with aggregate, per well values. Should contain: numeric column with measurmeents, string column with well names (e.g. 'A01', 'A02'), string vector with names of negative control wells, string vector with names of positive control wells.
in.col.meas	Numeric column with measurement.
in.col.well	Names of the column with well names (e.g. 'A01', 'A02').
in.wells.neg	Names of wells with negative controls (e.g. 'A01', 'A02').
in.wells.pos	Names of wells with positive controls (e.g. 'A01', 'A02').
in.wells.untr	Names of untreated wells (e.g. 'A01', 'A02'). Default, NULL. If not NULL, untreated wells will be excluded from mean and sd for z-score calculation.

Value

Data table with same columns as original but with columns npi and zscore added.

Examples

require(data.table)
dt = data.table(well = c('A01', 'A02', 'A03', 'B01', 'B02', 'B03', 'C01', 'C02', 'C03'),
                x = rnorm(9))
calcPlateStats(dt, 'x', 'well', 'B01', 'C03')

dmattek/hcs-package documentation built on May 16, 2019, 7:24 a.m.