finite_selection: Simulating single locus, two allele Mendelian populations...

In doublearon83/pop.gen.sims2: What the Package Does (One Line, Title Case)

Description

finite_selection simulates finite Mendelian populations with selection over many generations. Specify initial allele frequencies, population size, number of generations, selection coefficient, dominance coefficient, and number of replicates. The simulation produces each generation of the population by randomly selecting 2N (ND) alleles for N (ND) individuals from a gamete pool based on the allele frequencies as determined by the relative fitnesses of the genotypes.

Usage

finite_selection(s, h, p1g2_nr, p2g2_nr, alleles, ND_nr, generations_nr, n_rep)

Arguments

s	Selection coefficient
h	Dominance coefficient
p1g2_nr	Allele 1 frequency
p2g2_nr	Allele 2 frequency
alleles	Allele types (use 1 and 2)
ND_nr	Population size
generations_nr	Number of generations
n_reps	Number simulation replicates

Details

finite_selection returns three plots: 1) Allele 1 frequency versus number of generations, 2) Observed and expected heterozygosity (expected based on allele frequencies and drift) versus number of generations, and 3) Wright's F with a loess regression best fit line. It also returns Fisher's exact tests (fisher.test) comparing the observed genotype counts to the expected and initial values.

Examples

finite_selection(0.5,0.5,0.3,0.7,c(1,2),25,100,100)

doublearon83/pop.gen.sims2 documentation built on Dec. 20, 2021, 1:10 a.m.