scandal_cluster_markers_density: Compute cluster markers density

In dravishays/scandal: A framework for single-cell analysis

Description

This function computes the expression density of a set of marker genes for each cluster. The expression density is defined as the mean expression of the markers gene set accross all cells belonging to the same cluster.

Usage

scandal_cluster_markers_density(
  x,
  clusters,
  mname,
  markers,
  return_sorted = FALSE
)

Arguments

x	gene expression matrix
clusters	a character/factor vector of cluster assigment for each observation (column) in x
markers	a character vector of marker gene symbols corresponding to subset of genes (rows) in x
return_sorted	wether the result should be returned in descending order. Defaule is FALSE

Value

A tibble with two columns: Cluster and MCD (Markers Cluster Density).

Author(s)

Avishay Spitzer

dravishays/scandal documentation built on Jan. 8, 2020, 1:30 p.m.