searchPublished: Search for T cell receptor beta CDR3 amino acid sequences...

View source: R/searchPublished.R

searchPublishedR Documentation

Search for T cell receptor beta CDR3 amino acid sequences with known antigen specificity

Description

Search for published T cell receptor beta CDR3 amino acid sequences with known antigen specificity in a list of data frames.

Usage

searchPublished(study_table)

Arguments

study_table

A tibble generated by the LymphoSeq functions readImmunoSeq or productiveSeq. "junction_aa", "frequencyCount", and "count" are required columns.

Value

Returns a data frame of each repertoire_id name and instance in the repertoire_id that the published TCR sequence appeared along with additional information including antigen specificity, epitope, HLA type, and PubMed ID (PMID) for the reference where the sequence was characterized. The publishedTRB database is located in a separate package called LymphoSeqDB that should be loaded automatically.

See Also

Refer to the LymphoSeqDB package for details regarding the publishedTRB database.


elulu3/LymphoSeqTest documentation built on Aug. 27, 2022, 5:47 a.m.