README.md
In fosterlab/PrInCE-R: Predicting Interactomes from Co-Elution
PrInCE
PrInCE is a computational approach to infer protein-protein interaction networks from co-elution proteomics data, also called co-migration, co-fractionation, or protein correlation profiling. This family of methods separates interacting protein complexes on the basis of their diameter or biochemical properties. Protein-protein interactions can then be inferred for pairs of proteins with similar elution profiles. PrInCE implements a machine-learning approach to identify protein-protein interactions given a set of labelled examples, using features derived exclusively from the data. This allows PrInCE to infer high-quality protein interaction networks from raw proteomics data, without bias towards known interactions or functionally associated proteins, making PrInCE a unique resource for discovery.
For a detailed introduction to PrInCE, see the vignette:
browseVignettes("PrInCE")
fosterlab/PrInCE-R documentation built on Dec. 11, 2020, 3:51 p.m.
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
PrInCE
PrInCE is a computational approach to infer protein-protein interaction networks from co-elution proteomics data, also called co-migration, co-fractionation, or protein correlation profiling. This family of methods separates interacting protein complexes on the basis of their diameter or biochemical properties. Protein-protein interactions can then be inferred for pairs of proteins with similar elution profiles. PrInCE implements a machine-learning approach to identify protein-protein interactions given a set of labelled examples, using features derived exclusively from the data. This allows PrInCE to infer high-quality protein interaction networks from raw proteomics data, without bias towards known interactions or functionally associated proteins, making PrInCE a unique resource for discovery.
For a detailed introduction to PrInCE, see the vignette:
browseVignettes("PrInCE")
R Package Documentation
Browse R Packages
We want your feedback!
Note that we can't provide technical support on individual packages. You should contact the package authors for that.
Embedding an R snippet on your website
Add the following code to your website.
For more information on customizing the embed code, read Embedding Snippets.