normalize_modebetween_protein: Given some peptide-level matrix, normalize samples using...

View source: R/normalize_vwmb.R

normalize_modebetween_proteinR Documentation

Given some peptide-level matrix, normalize samples using foldchange mode-between at protein-level

Description

Given some peptide-level matrix, normalize samples using foldchange mode-between at protein-level

Usage

normalize_modebetween_protein(x, proteins, groups, rollup_algorithm = "maxlfq")

Arguments

x

numerical data matrix with log2 peptide abundances

proteins

array describing the grouping of the rows in x

groups

array describing the grouping of the columns in x

rollup_algorithm

algorithm for combining peptides to protein-level data, on which in subsequent steps the normalization/scaling factors will be computed. Refer to rollup_pep2prot function documentation for available options and a brief description of each

Value

normalized matrix x


ftwkoopmans/msdap documentation built on March 5, 2025, 12:15 a.m.