scaled_neg_log_hessian: Routine for computing the negative log-posterior Hessian for...

Description Usage Arguments Value

View source: R/posterior.R

Description

Routine for computing the negative log-posterior Hessian for the MASSIVE model

Usage

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scaled_neg_log_hessian(
  J,
  N,
  SS,
  sigma_G,
  param_list,
  prior_sd,
  n = 2,
  log_scale = TRUE
)

Arguments

J

Integer number of genetic instrumental variables.

N

Integer number of observations.

SS

Numeric matrix containing first- and second-order statistics.

sigma_G

Numeric vector of genetic IV standard deviations.

param_list

List of IV model parameter values.

prior_sd

List of standard deviations for the parameter Gaussian priors.

n

Integer number of alleles (trials) for the binomial genetic variants.

log_scale

Logical flag indicating whether scale parameters (sigma_X, sigma_Y) are given on the log-scale or on the normal scale.

Value

numeric matrix; negative log-posterior Hessian for the MASSIVE model.


igbucur/MASSIVE documentation built on Oct. 26, 2020, 1:26 a.m.