isglobal-brge/MADloy: Package to detect mosaic LOY from SNP array data

This packages is a suit of functions to perform association analysis of mosaic LOY and quantitative or continuous outcomes. It uses SNP array data in pennCNV format (e.g. having snp_name, chromosome, position, LRR, BAF and genotype). There are functions to perform quality control of samples, functions to process raw data and extract the LRR and BAF information of required genomic regions, and a function to perform calling based on Normal Inverse Gaussian distribution that properly fits LRR data.

install.packages("remotes")
remotes::install_github("isglobal-brge/MADloy")