This packages is a suit of functions to perform association analysis of mosaic LOY and quantitative or continuous outcomes. It uses SNP array data in pennCNV format (e.g. having snp_name, chromosome, position, LRR, BAF and genotype). There are functions to perform quality control of samples, functions to process raw data and extract the LRR and BAF information of required genomic regions, and a function to perform calling based on Normal Inverse Gaussian distribution that properly fits LRR data.
Package details |
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Author | Juan R Gonzalez |
Maintainer | Juan R Gonzalez <juanr.gonzalez@isglobal.org> |
License | GPL (>= 2) |
Version | 1.0.7 |
URL | https://github.com/isglobal-brge/MADloy and http://brge.isglobal.org |
Package repository | View on GitHub |
Installation |
Install the latest version of this package by entering the following in R:
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