Description Usage Arguments Value
getDownstreamNetwork - Create a network
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 | getDownstreamNetwork(
tissue = "mytissue",
n.iterations = 50,
min.exchanged.genes = 20,
expr.data,
beta = -1,
job.path = "~/tmp/",
min.cluster.size = 30,
net.type = "signed",
debug = F,
blockTOM = F,
save.tom = F,
save.plots = F,
excludeGrey = FALSE,
fullAnnotation = T,
silent = T
)
|
tissue |
A label to use to refer to the results in files and downstream results |
n.iterations |
Number of iterations in the k-means algorithm to refine the clustering process |
expr.data |
A data frame with expression data, ready to get into WGCNA. Columns are genes and rows are samples. Column names will be used as gene names in the analysis product |
beta |
The smoothing parameter of the WGCNA pipeline. If -1, then the method will suggest one automatically by looking at the R2 between gene connectivity and Scale Free Topology features |
job.path |
This method will generate a number of files. It needs a folder to write results |
min.cluster.size |
Minimum number of genes for a group to be considered as cluster for the tree cutting algorithm to convert from a dendogram to a cluster. |
net.type |
Whether a signed ("signed") or unsigned ("unsigned") network type will be created |
debug |
Set this to true if you want a quick run of the method to test how it works with a small amount of your genes |
excludeGrey |
If WGCNA detects grey genes, set it to TRUE if you want them removed from the network before applying k-means |
A file name that can be used to access your network
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