addNetworkToDDBB: Title

Description Usage Arguments Value

View source: R/netdb.R

Description

Title

Usage

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addNetworkToDDBB(
  netf,
  folder,
  which.one,
  tissue,
  rewrite = F,
  filter = c("GO", "KEGG", "REAC", "HP"),
  ensembl = TRUE,
  do.go = T,
  do.ct = T,
  exclude.iea = T,
  correction.method = "gSCS",
  organism = "hsapiens",
  out.file = paste0(netf, "_gprofiler.csv")
)

Arguments

netf

The RDS file produced by getDownstreamNetwork()

folder

This method will produce enrichment files. This variable indicates where to store them

which.one

Category under which the network should be installed. If new, the category will be created

tissue

A label to designate the network under the category

rewrite

If TRUE and the network is already added with that name under the category, it is overwritten with the new material

filter

gProfiler parameter to indicate which annotation databases to use when assessing for enrichment at the network modules

ensembl

Whether the gene names are indicated as Ensembl ids or Symbols

do.go

If FALSE the annotation databases enrichment is not perfomed

do.ct

If FALSE the cell enrichment is not performed. Note that cell enrichment works fine for brain. Not so good for other tissues or conditions.

exclude.iea

gProfiler parameter to indicate that if FALSE, inferred annotations from GO are not used

correction.method

gProfiler parameter to indicate the p.value adjustment method

organism

gProfiler parameter to indicate the organism upon which genes are defined

out.file

Optional file to allocate the GO enrichment

Value

This method updates the global variable coexp.nets with a new entry to it can be used with the rest of methods of the package


juanbot/CoExpNets documentation built on May 15, 2021, 12:20 p.m.