rkimura: The Kimura distribution

In lbozhilova/kimura: Fitting Kimura Distirbutions to Heteroplasmy Data

The Kimura distribution

Description

Generate random samples from the Kimura(p, b) distribution.

Usage

rkimura(n, p, b)

Arguments

n	number of observations to generate.
p	number in (0; 1): initial heteroplasmy.
b	number in (0; 1): drift parameter.

Value

A vector of length n of heteroplasmy fractions generated from the Kimura(p, b) distribution. Note that while most real-life heteroplasmy fraction data is rounded to 2 significant digits, these randomly generated values are not.

References

Wonnapinij, Passorn, Patrick F. Chinnery, and David C. Samuels. "The distribution of mitochondrial DNA heteroplasmy due to random genetic drift." The American Journal of Human Genetics 83.5 (2008): 582-593.

Examples

rkimura(10, 0.3, 0.5)

lbozhilova/kimura documentation built on May 7, 2023, 12:07 p.m.