andreyev2010 | R Documentation |
Data from Andreyev AY, Shen Z, Guan Z, Ryan A, Fahy E, Subramaniam S, Raetz CR, Briggs S, Dennis EA. Application of proteomic marker ensembles to subcellular organelle identification. Mol Cell Proteomics. 2010 Feb;9(2):388-402. DOI:http://dx.doi.org/10.1074/mcp.M900432-MCP200. PubMed PMID:19884172; PubMed Central PMCID:PMC2830848.
The 6 subcellular fractions are nuclei, mitochondria, cytoplasm, endoplasmic reticulum, plasma membrane and dense microsomal fraction.
data("andreyev2010")
data("andreyev2010rest")
data("andreyev2010activ")
andreyev2010
is the full data where missing values were
replaced by 0. andreyev2010rest
and andreyev2010activ
contain the resting (control) and Kdo2-lipid A-treated (activated)
data respectively, which have been normalised (each reporter intensity
was normalised by the sum over all replicates).
These data were generated from supplemental tables S1 (quantitative
data) and 2 (organelle markers)
(http://www.mcponline.org/content/9/2/388/suppl/DC1). See
inst/scripts/andreyev2010.R
for details.
data(andreyev2010rest, verbose = TRUE)
data(andreyev2010activ, verbose = TRUE)
library("pRoloc")
par(mfrow = c(1, 2))
plot2D(andreyev2010rest, main = "Resting (control)")
plot2D(andreyev2010activ, main = "Kdo2-lipid A-treated")
addLegend(andreyev2010activ)
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