SignatureQBiC: Generate GR and LR for a TF-signature pair (Signature-QBiC)

Description Usage Arguments Value

View source: R/SignatureQBiC.R

Description

SignatureQBiC model. This function generates Gain Ratio and Loss Ratio for a TF (represented by universal PBM) with a mutational signature (or a mutation spectrum)

Usage

1
SignatureQBiC(QBiC_score_file_path, pvalue_file_path, sig, plot.path = NULL)

Arguments

QBiC_score_file_path

All QBiC scores for a universal PBM. The file can be downloaded from http://qbic.genome.duke.edu/downloads

pvalue_file_path

p_values for all twelvemers. The file can be downloaded from http://qbic.genome.duke.edu/downloads

sig

A one-column matrix contains probability of each mutation types with row.names set to SigQBiC::mut_types.

Value

A list containing GR and LR.


liumoLM/SigQBiC documentation built on Feb. 5, 2021, 12:53 a.m.