multittest: multittest

In mjhelf/Mosaic: Metaboseek platform

multittest

Description

Calculate per-row t-test between grouped columns of a data.frame.

Usage

multittest(
  df,
  groups,
  ttest = TRUE,
  adjmethod = "bonferroni",
  controlGroup = NULL
)

Arguments

df	a data.frame with numeric (intensity) values
groups	named list of intensity columns listed by group (as supplied by $anagroupnames or $anagroupnames_norm of MseekFT objects)
ttest	if TRUE, ttest will be calculated
adjmethod	method to adjust p values (passed on to stats::p.adjust)
controlGroup	name of the control group in groups. If NULL, all groups will be compared against all samples outside the group.

Details

columns in the export data.frame. All columns are generated for each group defined in groups, where GX is replaced by the group name:

• GX__CV Coefficient of variation (relative standard deviation (sd/mean)) within the group

• GX__pval p value between this group and all samples in all other groups, as calculated by t.test()

• GX__pval_adj p values, adjusted by the selected adjmethod using p.adjust()

Value

a data.frame with same number of rows as df, with coluns as described in details

mjhelf/Mosaic documentation built on April 28, 2022, 11:32 a.m.