binaryRegulation: Binary CREs in Local Heterogeneous Network

In mortyran/NetLCP: Prioritizing combinations of regulatory elements in the heterogeneous network with variant ‘switches’ detection

Binary CREs in Local Heterogeneous Network

Description

Locate the binary CREs in regional Heterogeneous network which are experimentally verified.

Usage

binaryRegulation(elmentList, regulationType, allRegulation)

Arguments

elmentList	a vector consist of elements including circRNA, lncRNA, miRNA ,mRNA or KEGG/Reactome/Wikipathway pathway IDs.
regulationType	character string naming the types of CREs which can be located including "circRNA-miRNA", "lncRNA-miRNA", "lncRNA-mRNA", "miRNA-mRNA", "miRNA-pathway", "mRNA-pathway".
allRegulation	a logical value indicates exploring all related CREs from the storage (TRUE) or internal CREs between input elements (FALSE).

Value

The dataframe of regulatory data with the colnames of Node1, Node2, Datasoure and RegulationType.

Examples

binaryRegulation(elmentList = c("2309", "3838", "MIMAT0000255"), regulationType = "miRNA-mRNA",  allRegulation = FALSE)

mortyran/NetLCP documentation built on Feb. 26, 2023, 11:33 a.m.