flywire_synapse_simplify: Collapse Buhmann predicted flywire synapses into smaller...

In natverse/hemibrainr: Code for Working with Data from Janelia FlyEM's Hemibrain Project and the flywire data sets``

Collapse Buhmann predicted flywire synapses into smaller units

Description

Many predicted Buhmann synapses may be located at one real synapse. Collapse Buhmann predicted flywire synapses into smaller units using a hierarchical clustering based on the Euclidean distances between predicted 'presynapses'.

Usage

flywire_synapse_simplify(
  x,
  method = c("cleft_scores", "scores", "mean"),
  collapse = TRUE,
  fast = TRUE
)

Arguments

x	a data.frame of synapses for FlyWire neurons, as generated by, for example, fafbseg::flywire_partners.
method	when synapses are collapsed, they are either represented by the predicted synapse amongst them with the best score, cleft_score or a mean of the meat data for each of these predicted synapses.
collapse	logical, whether or not to collapse synapses in the same cluster to a single synapse. If FALSE then cluster groupings are given in the returned data.frame.
fast	logical, whether or not to use fastcluster::hclust rather than stats::hclust to cluster synapses.

Value

a data.frame of collapsed synapses.

See Also

flywire_googledrive_data

Examples

## Not run: 
syns=fafbseg::flywire_partners("720575940621039145")
syns.simp = flywire_synapse_simplify(syns)

## End(Not run)

natverse/hemibrainr documentation built on Nov. 27, 2024, 9:01 p.m.