rxPp: Simulate a from a Poisson process

In nlmixrdevelopment/RxODE: Facilities for Simulating from ODE-Based Models

Simulate a from a Poisson process

Description

Simulate a from a Poisson process

Usage

rxPp(
  n,
  lambda,
  gamma = 1,
  prob = NULL,
  t0 = 0,
  tmax = Inf,
  randomOrder = FALSE
)

Arguments

n	Number of time points to simulate in the Poisson process
lambda	Rate of Poisson process
gamma	Asymmetry rate of Poisson process. When gamma=1.0, this simulates a homogenous Poisson process. When gamma<1.0, the Poisson process has more events early, when gamma > 1.0, the Poisson process has more events late in the process. When gamma is non-zero, the tmax should not be infinite but indicate the end of the Poisson process to be simulated. In most pharamcometric cases, this will be the end of the study. Internally this uses a rate of: l(t) = lambdagamma(t/tmax)^(gamma-1)
prob	When specified, this is a probability function with one argument, time, that gives the probability that a Poisson time t is accepted as a rejection time.
t0	the starting time of the Poisson process
tmax	the maximum time of the Poisson process
randomOrder	when TRUE randomize the order of the Poisson events. By default (FALSE) it returns the Poisson process is in order of how the events occurred.

Value

This returns a vector of the Poisson process times; If the dropout is >= tmax, then all the rest of the times are = tmax to indicate the dropout is equal to or after tmax.

Author(s)

Matthew Fidler

Examples

## Sample homogenous Poisson process of rate 1/10
rxPp(10, 1 / 10)

## Sample inhomogenous Poisson rate of 1/10

rxPp(10, 1 / 10, gamma = 2, tmax = 100)

## Typically the Poisson process times are in a sequential order,
## using randomOrder gives the Poisson process in random order

rxPp(10, 1 / 10, gamma = 2, tmax = 10, randomOrder = TRUE)

## This uses an arbitrary function to sample a non-homogenous Poisson process

rxPp(10, 1 / 10, prob = function(x) {
  1 / x
})

nlmixrdevelopment/RxODE documentation built on April 10, 2022, 5:36 a.m.