dCell.run: Run Decon-cell to generate new gene signature and...

Description Usage Arguments Value Examples

View source: R/dCell_functions.R

Description

Run Decon-cell to generate new gene signature and characterize marker genes. dCell.run Runs dCell.run to generate gene expression signatures to predict cell proportions of bulk tissues

Usage

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dCell.run(exp, proportions, iterations = 10)

Arguments

exp

A matrix or data.frame of normalized (by gene lenght and library size (RPKM, TMM, TPM...)) and scaled expression data, samples by columns and genes by row. Preferably comming from dCell.expProcessing.

proportions

A matrix or data.frame of cell proportions within each bulk RNA-Seq sample. Samples by row and cell types by column.

iterations

Number of iterations (and models) which would be calculated

test.size

Proportion of samples to be considered as test, 100 - test.size would be considered de proportion used for training.

Value

a dCell.models-like object, a list (with a length == ncol(proportion.mat)), each element of the list contains the number of models defined by iterations

Examples

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raguirreg/DeconCell documentation built on May 29, 2019, 8:05 a.m.