data_halagappa: Halagappa - Ch14 - from Halagappa et al. (2007)
In rcalinjageman/esci: Estimation Statistics with Confidence Intervals

data_halagappa

R Documentation

Halagappa - Ch14 - from Halagappa et al. (2007)

Description

Could eating much less delay Alzheimer's? If so, that would be great news. Halagappa et al. (2007) investigated the possibility by using a mouse model, meaning they used Alzheimer-prone mice, which were genetically predisposed to develop neural degeneration typical of Alzheimer's. The researchers used six independent groups of mice, three tested in mouse middle age when 10 months old, and three in mouse old age when 17 months. At each age there was a control group of normal mice that ate freely (the NFree10 and NFree17 groups), a group of Alzheimer-prone mice that also ate freely (the AFree10 and AFree17 groups), and another Alzheimer-prone group restricted to 40% less food than normal (the ADiet10 and ADiet17 groups). Table 14.2 lists the factors that define the groups, and group labels. I'll discuss one measure of mouse cognition: the percent time spent near the target of a water maze, with higher values indicating better learning and memory. Table 14.2 reports the means and standard deviations for this measure, and group sizes.