Do the reverse translation from amino acids back to DNA nucleotides, using a reference DNA sequence as a source of codon usage frequency.
A character string of valid amino acids.
A character string of DNA, in frame, usually large, that represents the typical codon usage frequency.
Since the mapping from AA to DNA is not unique, the user provides a chunk of DNA reference, that will be converted to AA and used to model the frequency distribution for randomly selecting DNA codons from each amino acid.
a character string, of length
nchar(aa) * 3, of DNA that is a valid reverse translation
of the given amino acid string.
Passes the frequency distribution of codons found in
sample, to randomly
select codons with a usage frequency similar to the given reference DNA.
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