new_covariate: New covariate

Description Usage Arguments

View source: R/new_covariate.R

Description

Describe data for a covariate, either fixed or time-variant

Usage

1
2
3
new_covariate(value = NULL, times = NULL, implementation = "interpolate",
  unit = NULL, interpolation_join_limit = 1, remove_negative_times = TRUE,
  comments = NULL, verbose = TRUE)

Arguments

value

a numeric vector

times

NULL for time-invariant covariate or a numeric vector specifying the update times for the covariate

implementation

for time-varying covariates either 'LOCF' (last observation carried forward) or 'interpolate' (default)

unit

specify covariate unit (optional, for documentation purposes only)

interpolation_join_limit

for 'interpolate' option, if covariate timepoints are spaced too close together, the ODE solver sometimes chokes. This argument sets a lower limit on the space between timepoints. It will create average values on joint timepoints instead. If undesired set to NULL or 0.

remove_negative_times

'TRUE“ or 'FALSE'

comments

'NULL', or vector of length equal to 'value' specifying comments to each observation

verbose

verbosity


ronkeizer/PKPDsim documentation built on May 27, 2019, 1:50 p.m.