sigven/oncoEnrichR: Functional annotation and enrichment analysis of genesets in the context of cancer

oncoEnrichR performs annotation and prioritization of genesets discovered from high-throughput experiments within cancer biology. The tool queries a number of high-quality resources, including Project Score (cellular fitness in genome-scale drop-out screens), Open Targets Platform (comprehensive target-drug and target-disease associations), TCGA (genetic aberrations and gene expression patterns in human tumor samples), STRING (protein-protein interaction networks), CORUM (curated protein complexes), COMPPI (subcellular compartments), Human Protein Atlas (tissue and cell-type specific expression patterns and prognostic associations), and Gene Ontology/MSigDB/REACTOME/KEGG (functional enrichment/over-representation analysis with respect to gene function and cellular pathways). The package outputs both an interactive HTML report and an Excel workbook in which the user can interrogate the various types of annotations and analyses performed with the geneset.

Getting started

Package details

AuthorSigve Nakken
MaintainerSigve Nakken <sigven@ifi.uio.no>
LicenseMIT
Version0.8.8
URL https://github.com/sigven/oncoEnrichR
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
install.packages("remotes")
remotes::install_github("sigven/oncoEnrichR")
sigven/oncoEnrichR documentation built on Feb. 28, 2021, 1:43 p.m.