README.md

In smvargas/PERMANOVA: Power estimation for microbiome studies using pairwise distances and PERMANOVA.

micropower

The micropower package is designed to facilitate power estimation for microbiome studies that will be analyzed with pairwise distances (beta diversity) and PERMANOVA (a non-parametric extension of multivariate analysis of variance to a matrix of pairwise distances).

It includes: + tools to perform distance matrix simulation to model within-group pairwise distances according to pre-specified population parameters + a method to incorporate effects of different sizes within a simulated distance matrix + a bootstrap method for estimating PERMANOVA power from simulated distance matrices

A detailed description of the methods underlying the micropower package has been submitted for publication. Please see: Kelly BJ, Gross R, Bittinger K, Sherrill-Mix S, Lewis JD, Collman RG, Li H, Bushman FD. Power and sample-size estimation for microbiome studies using pairwise distances and PERMANOVA. A line I wrote in my computer

smvargas/PERMANOVA documentation built on May 20, 2019, 12:37 p.m.