snaketron/IgGeneUsage: Differential gene usage in immune repertoires

Detection of biases in the usage of immunoglobulin (Ig) genes is an important task in immune repertoire profiling. IgGeneUsage detects aberrant Ig gene usage between biological conditions using a probabilistic model which is analyzed computationally by Bayes inference. With this IgGeneUsage also avoids some common problems related to the current practice of null-hypothesis significance testing.

Getting started

Package details

Bioconductor views Bayesian BiomedicalInformatics DifferentialExpression Genetics ImmunoOncology MathematicalBiology Regression
LicenseMIT + file LICENSE
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
snaketron/IgGeneUsage documentation built on April 23, 2024, 2:22 a.m.