snaketron/IgGeneUsage: Differential gene usage in immune repertoires

Decoding the properties of immune repertoires is key in understanding the response of adaptive immunity to challenges such as viral infection. One important task in immune repertoire profiling is the detection of biases in Ig gene usage between biological conditions. IgGeneUsage is a computational tool for the analysis of differential gene usage in immune repertoires. It employs Bayesian hierarchical models to fit complex gene usage data from immune repertoire sequencing experiments and quantifies Ig gene usage biases as probabilities.

Getting started

Package details

Bioconductor views Bayesian DifferentialExpression Genetics Regression
Licensefile LICENSE
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
snaketron/IgGeneUsage documentation built on Nov. 12, 2019, 6:46 a.m.