Description Usage Arguments Details Examples
View source: R/tuning_proposals.R
Maximum likelihood estimate without regularization.
1 2 | unregularized_mle(fct_list, starts = data.frame(alpha = c(0.01, 0.01),
delta = c(0.01, 1e-04)), multiplier = 20, c_seq_len = 96, ...)
|
fct_list |
A list of frequency count tables, assumed to be biological replicates. |
starts |
Starting values for |
multiplier |
The upper bound of the grid of candidate C values, stated in terms of a multiple of the maximum observed richess (c). For example if c is 50 and multiplier is 10, the method evaluates the likelihood in a C grid from 50 to 500. |
c_seq_len |
The number of points in the C grid search. |
This is used as the comparison point for our tuning proposals
and amounts to a wrapper for direct_optimise_replicates
. The
output selected_lambda
is always NA for this method, but we format
in this way for consistency with methods 1-4.
1 | unregularized_mle(nb_fct_simulation(100, 0.1, 0.1, 2))
|
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