metTFNet.multi: Target network of multiple methyl-regulationg TF

In takahirosuzuki0626/mTFTarget:

Description

This function draws a DNA methylation regulatory network conposed of methyl-regulating TF, target promoter, target enhancer, and enhancer connected genes This fanction is designed for multiple methyl-regulating TF input. output "TF_methyl_network.pdf" and connection dataframe

Usage

metTFNet.multi(MethylDemethyl = "Demethyl",
  eg_connection_list = eg_connection_list,
  sig_genes_list = sig_genes_list, outname = "")

Arguments

MethylDemethyl	a vector. methylation or demethylation mediated by the methyl-regulating TF. "Methyl" or "Demethyl"
eg_connection_list	a list of connection data between enhancers of the methyl-regulating TF targets and thir downstream gene. the data have to have score at 3rd column.
sig_genes_list	a list of vectors of the methyl-regulating TF target promoters
outname	name for output file

Value

a dataframe of connections (and export a network plot as a pdf)

takahirosuzuki0626/mTFTarget documentation built on Jan. 4, 2022, 9:44 a.m.