MotPosiList: Motif position list at DMRs

Description Usage Arguments Value

View source: R/MotPosiList.R

Description

This function performes differentially methylation analysis and motif enrichment analysis at the DMR

Usage

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MotPosiList(infile = "sel_processed_Mval.txt", motifDBList,
  ControlColnum, TreatmentColnum, p.cutoff = 0.001, cutoff = 2,
  MethylDemethyl = "Demethyl", version = "850", sampling = FALSE,
  seq_range = c(-200, 200), outname = "motif_num_dist",
  nbiom_cutoff = 0.05)

Arguments

infile

input m-value file

motifDBList

list of motif PWM

ControlColnum

control column index(s)

TreatmentColnum

treatment column index(s)

p.cutoff

cutoff for multi-sample comarison (p-value)

cutoff

cutoff for single sample comparison (delta M)

MethylDemethyl

Metylation or Demethylation analysis

version

version of methylation array 450 or EPIC(850)

sampling

number of sampling. if FALSE, use all data

seq_range

range from CpG to be analyzed

outname

output file name

nbiom_cutoff

cutoff of negative binomial model test

Value

a List of lists of motif positions in DMR from CpG sites and of that in random regions


takahirosuzuki0626/mTFTarget documentation built on Jan. 4, 2022, 9:44 a.m.