Description Usage Arguments Value
This function performes differentially methylation analysis and motif enrichment analysis at the DMR
1 2 3 4 5 | MotPosiList(infile = "sel_processed_Mval.txt", motifDBList,
ControlColnum, TreatmentColnum, p.cutoff = 0.001, cutoff = 2,
MethylDemethyl = "Demethyl", version = "850", sampling = FALSE,
seq_range = c(-200, 200), outname = "motif_num_dist",
nbiom_cutoff = 0.05)
|
infile |
input m-value file |
motifDBList |
list of motif PWM |
ControlColnum |
control column index(s) |
TreatmentColnum |
treatment column index(s) |
p.cutoff |
cutoff for multi-sample comarison (p-value) |
cutoff |
cutoff for single sample comparison (delta M) |
MethylDemethyl |
Metylation or Demethylation analysis |
version |
version of methylation array 450 or EPIC(850) |
sampling |
number of sampling. if FALSE, use all data |
seq_range |
range from CpG to be analyzed |
outname |
output file name |
nbiom_cutoff |
cutoff of negative binomial model test |
a List of lists of motif positions in DMR from CpG sites and of that in random regions
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