Compares the fit of the depth-adjusted negative binomial model and basic negative binomial model.
a numeric matrix of raw UMI counts, columns = samples, rows = genes.
a calculated size factor for library size normalization.
Compares the fit of the depth-adjusted negative binomial model and basic negative binomial model. Depth -adjusted negative binomial is fit to raw molecule counts. Basic negative binomial is fit to library-size normalized counts. The absolute error between observed gene-specific dropouts and expectations given each model is calculated. And a plot of fitted and observed mean-expression vs dropouts is created.
A named list containing: errors : Vector of errors for each model. basic_fit : object for the basic negative binomial. adjusted_fit : object for the depth-adjusted negative binomial.
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