tallulandrews/M3D: Michaelis-Menten Modelling of Dropouts in single-cell RNASeq

This package fits a Michaelis-Menten model to the pattern of dropouts in single-cell RNASeq data. This model is used as a null to identify significantly variable (i.e. differentially expressed) genes for use in downstream analysis, such as clustering cells.

Getting started

Package details

AuthorTallulah Andrews <tallulandrews@gmail.com>
Bioconductor views DifferentialExpression DimensionReduction FeatureExtraction GeneExpression RNASeq Sequencing Software Transcriptomics
MaintainerTallulah Andrews <tallulandrews@gmail.com>
LicenseGPL (>=2)
URL https://github.com/tallulandrews/M3Drop
Package repositoryView on GitHub
Installation Install the latest version of this package by entering the following in R:
tallulandrews/M3D documentation built on May 31, 2019, 2:55 a.m.