adiponectin.scores: Genetic risk score for adiponectin and effects on coronary...

In tobyjohnson/gtx: Genetics ToolboX

Description

Risk scores parameterised using GWAS meta-analysis results published by the ADIPOGen consortium (Dastani et al. PLoS Genetics 2012) for adiponectin, and effects on coronary artery disease from the CARDIoGRAM consortium and published by Dastani et al. (Atherosclerosis 2013).

Usage

data(adiponectin.scores)

Format

A data frame suitable for use with other functions in this package, see gtx.params.

The score using only 17 independent SNPs is called Adiponectin2013, and the “coef” is defined only for these SNPs. Effect size coefficients for adiponectin (for all 162 SNPs) and for CAD (where available) are taken from Tables S1 and S2 of Dastani et al. (2013).

Source

For the publication by Dastani et al. from which these data were extracted see http://dx.doi.org/10.1016/j.atherosclerosis.2013.03.034.

Examples

data(adiponectin.scores)
with(subset(adiponectin.scores, score == "Adiponectin2013"),
  grs.plot(beta_Adiponectin, beta_CAD, se_CAD, text = locus))

tobyjohnson/gtx documentation built on Aug. 30, 2019, 8:07 p.m.