read.snpdata.minimac: Read genotype dosages in the format output by minimac

Description Usage Arguments Details Value Author(s) References

View source: R/input.R

Description

Reads snp coding information and genotype data from paired .info.gz and .dose.gz files, as generated by the MACH and minimac genotype imputation programs, and returns the data in a standard format (see snpdata) that can be used by other functions in this package.

Usage

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read.snpdata.minimac(fileroot, tol.af = 0.01, phenotypes = NULL,
                  isuffix = ".info.gz", dsuffix = ".dose.gz")

Arguments

fileroot

a filename root to which suffixes (my default .info.gz and .dose.gz) will be appended.

tol.af

a tolerence for checking allele frequencies between the two files read.

phenotypes

if not NULL, a data frame of phenotypes to be merged with the genotypes; must contain a column called MACHID which is used to match against the first column of the mldose file.

isuffix

a suffix to add to the filename root to make the name of the info file

dsuffix

a suffix to add to the filename root to make the name of the dosage file

Details

This function is just a wrapper for read.snpdata.mach with different default isuffix and dsuffix arguments.

Value

Returns a list with snpinfo and data slots, see snpdata.

Author(s)

Toby Johnson Toby.x.Johnson@gsk.com

References

Information about the MACH and minimac programs for genotype imputation, including their output formats, can be found at http://www.sph.umich.edu/csg/abecasis/MACH.


tobyjohnson/gtx documentation built on Aug. 30, 2019, 8:07 p.m.