neuralgia: Treatment of post-herpetic neuralgia.

In trobinj/trtools: Miscellaneous Tools for Teaching Statistics

Treatment of post-herpetic neuralgia.

Description

These data are from a study in which patients with post-herpetic neuralgia were randomly assigned to receive iontophoresis of either vincristine or saline. The patients were interviewed six weeks after treatment to determine if there was any improvement in the neuralgia.

Usage

neuralgia

Format

A data frame of 18 observations and five variables.

pain:

reported pain cessation at six weeks

treatment:

treatment condition (vincristine or saline)

age:

patient age (in years) at treatment

sex:

patient sex

complaint:

duration (months) of pre-treatment complaint

Note

The data are from Layman, Agyras, and Glynn (1986) and were featured in Piegorsch (1992) as an example of data for a generalized linear model with a complementary log-log link function since time to pain cessation was thought to follow an approximate exponential distribution. One issue with these data is that they appear to suffer from separation and models with treatment are not estimable, although this was not reported by Piegorsch (1992).

Source

Layman, P. R., Argyras, E., & Glynn, C. J. (1986). Iontophoresis of vincristine versus saline in post-herpetic neuralgia. A controlled trial. Pain, 25, 165-170.

Piegorsch, W. W. (1992). Complementary log-log regression for generalized linear models. The American Statistician, 46, 94-99.

trobinj/trtools documentation built on Jan. 28, 2024, 3:20 a.m.