Description Usage Arguments Value Author(s) References Examples
Calculate group-level summaries based solely on raw data (i.e., that do not require any modeling).
1 2 3 4 5 6 7 8 9 10 11 12 13 | tally_study(
study_data_frame,
group_name = maeve_options("group_name"),
subject_ID = maeve_options("subject_ID"),
x_name = maeve_options("x_name"),
endpoint_name = maeve_options("endpoint_name"),
reference = levels(study_data_frame[, group_name])[1],
response = c("none", "PR", "EOS_CR", "PR_or_EOS_CR")[1],
EOS_CR_minval = maeve_options("EOS_CR_minval"),
PR_threshold = maeve_options("PR_threshold"),
additive_offset = 0.5,
na.rm = TRUE
)
|
study_data_frame |
a well-prepared data.frame with the study data and appropriate columns. |
group_name |
character name of treatment regimen factor |
subject_ID |
character identifier for individual within a group. |
x_name |
character name of independent variable (usually time or concentration). |
endpoint_name |
character name of dependent variable (e.g., tumor volume, body weight). |
reference |
character name of designated reference group. Must be a level from the factor named by group_name. |
response |
character name of by-group count summary. |
EOS_CR_minval |
numeric passed to internal function to decide what constitutes a "complete response" for the the End-Of-Study Complete Response (EOS_CR) value on the original, untransformed response scale. |
PR_threshold |
numeric passed to internal function to decide what constitutes a "partial response" for the PR value. Fractional reduction is computed by-ID, from an ID-specific baseline value on the original, untransformed scale. |
additive_offset |
numeric value to add to each count in a 2 x 2 table before computing log odds ratio. Default gives the Haldane-Ascombe-Gart correction of adding 0.5 to every count. |
na.rm |
logical whether to remove NA values when computing summaries. |
An R data.frame with one row per group.
Bill Forrest <forrest@gene.com>
Bill Forrest forrest@gene.com
1 | vismo_tally <- tally_study( vismodegib )
|
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