myco: Association between leprosy and BCG vaccination

In survey: Analysis of Complex Survey Samples

Association between leprosy and BCG vaccination

Description

These data are in a paper by JNK Rao and colleagues, on score tests for complex survey data. External information (not further specified) suggests the functional form for the Age variable.

Usage

data("myco")

Format

A data frame with 516 observations on the following 6 variables.

Age

Age in years at the midpoint of six age strata

Scar

Presence of a BCG vaccination scar

n

Sampled number of cases (and thus controls) in the age stratum

Ncontrol

Number of non-cases in the population

wt

Sampling weight

leprosy

case status 0/1

Details

The data are a simulated stratified case-control study drawn from a population study conducted in a region of Malawi (Clayton and Hills, 1993, Table 18.1). The goal was to examine whether BCG vaccination against tuberculosis protects against leprosy (the causative agents are both species of _Mycobacterium_). Rao et al have a typographical error: the number of non-cases in the population in the 25-30 age stratum is given as 4981 but 5981 matches both the computational output and the data as given by Clayton and Hills.

Source

JNK Rao, AJ Scott, and Skinner, C. (1998). QUASI-SCORE TESTS WITH SURVEY DATA. Statistica Sinica, 8(4), 1059-1070.

Clayton, D., & Hills, M. (1993). Statistical Models in Epidemiology. OUP

Examples

data(myco)
dmyco<-svydesign(id=~1, strata=~interaction(Age,leprosy),weights=~wt,data=myco)

m_full<-svyglm(leprosy~I((Age+7.5)^-2)+Scar, family=quasibinomial, design=dmyco)
m_age<-svyglm(leprosy~I((Age+7.5)^-2), family=quasibinomial, design=dmyco)
anova(m_full,m_age)

## unweighted model does not match
m_full
glm(leprosy~I((Age+7.5)^-2)+Scar, family=binomial, data=myco)

survey documentation built on Aug. 28, 2024, 3 a.m.