mouse.data is an ExpressionSet object where exprs slot carries the mouse gene expression data and pData carries the phenotype data.
This mouse.data is a subset taken from our published mouse data (Johnson et al. 2010). The original full mouse data was profiled by affymetrix 430 v2(mRNA). It contains 45037 probe-sets for 13 mice brain tumors and 179 normal mice stem cells.
We used the best-match data (available from www.affymetrix.com) as the mapping data of ortholog-matched probe-sets across human gene expression data and mouse gene expression data. expr slot of mouse.data is a matrix of subset of the full mouse gene expression data. Those selected mouse probe-sets are ortholog-matched with human probe-sets in human.data. pData slot of the mouse.data is a data frame with row representing mouse samples and two columns indicating sample IDs and sample group labels for each sample (either "mouse.tumor" or "mouse.control").
A matrix with 264 rows and 192 columns with rows representing probe-sets and cloumns of mouse sample IDs. Each row name of the matrix is a probe-set Identifier.
A data frame with 192 rows and 2 columns. Each row represents one mouse sample. Column id is the mouse sample ID and grp is the assigned sample group label.
R. Johnson et al.(2010) Cross-species genomics matches driver mutations and cell compartments to model ependymoma. Nature, 466: 632-6.
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