plotOptimResults: Plot the data and simulated values
In CellNOptR: Training of boolean logic models of signalling networks using prior knowledge networks and perturbation data

Description Usage Arguments Details Value Author(s) References See Also Examples

This function is the equivalent of CNOPlotFits, it plots the data and the simulated values, along with an image plot that tells which cues were present. The plots are coloured according to the fit between data and simulated data.

1 2	plotOptimResults(simResults, expResults, times, namesCues, namesSignals, valueCues, formalism="new")

`simResults`	a list with a field for each time point, each containing a matrix of dimensions (number of conditions) * (number of signals), with the first field being t0. Typically produced by simulating a model and then extracting the columns that correspond to signals
`expResults`	same as above, but contains the experimental results, ie this is `CNOlist$valueSignals`
`times`	a vector of times, its length should be the same as the number of fields in simResults and ExpResults
`namesCues`	a vector of names, typically `CNOlist$namesCues`
`namesSignals`	a vector of names, typically `CNOlist$namesSignals`
`valueCues`	a matrix of dimensions (number of conditions) * (number of cues), typically `CNOlist$valueCues`
`formalism`	New convention is to take the time=0 data set into account to compute the MSE. you can use the previous convetion by setting this argument to something different from the default value.

The colouring of the background is done as follows: the mean absolute difference between observed and simulated values are computed, and colours are chosen based on this value: red (above 0.9), indianred1 (between O.8 and 0.9), lightpink2 (between 0.7 and 0.8), lightpink (between 0.6 and 0.7), mistyrose (between 0.5 and 0.6), palegoldenrod (between 0.4 and 0.5), palegreen (between 0.3 and 0.4), darkolivegreen3 (between 0.2 and 0.3), chartreuse3 (between 0.1 and 0.2), forestgreen (between 0 and 0.1). This function is used inside cutAndPlotResultsT1.

This function doesn't return anything, it just produces a plot in your graphics window.

C. Terfve

J. Saez-Rodriguez, L. G. Alexopoulos, J. Epperlein, R. Samaga, D. A. Lauffenburger, S. Klamt and P. K. Sorger. Discrete logic modeling as a means to link protein signaling networks with functional analysis of mammalian signal transduction, Molecular Systems Biology, 5:331, 2009.

cutAndPlotResultsT1

#We will plot the fit of the full initial model compared to the data, without any optimisation
#This is normally not done on a stand alone basis, but if you have a model and would like to visualise its output compared to your data, then this is what you should do

#load and prepare data

data(CNOlistToy,package="CellNOptR")
data(ToyModel,package="CellNOptR")
indicesToy<-indexFinder(CNOlistToy,ToyModel,verbose=TRUE)
ToyFields4Sim<-prep4sim(ToyModel)

#simulate model

simRes<-simulatorT1(CNOlist=CNOlistToy,model=ToyModel, simList=ToyFields4Sim, indexList=indicesToy)

#format data and results

simResults<-list(t0=matrix(data=0,nrow=dim(simRes)[1],ncol=dim(simRes)[2]),t1=simRes)
expResults<-list(t0=CNOlistToy$valueSignals[[1]],t1=CNOlistToy$valueSignals[[2]])

#plot

plotOptimResults(
	simResults=simResults,
	expResults=expResults,
	times=CNOlistToy$timeSignals[1:2],
	namesCues=CNOlistToy$namesCues,
	namesSignals=CNOlistToy$namesSignals,
	valueCues=CNOlistToy$valueCues)