Differential binding analysis of ChIP-seq peaksets
Computes differentially bound sites from multiple ChIP-seq experiments using affinity (quantitative) data. Also enables occupancy (overlap) analysis and plotting functions.
Entry Points:
dba: | Construct a dba object |
dba.peakset: | Add a peakset to, or retrieve a peakset from, a dba object |
dba.overlap: | Compute binding site overlaps and/or correlations |
dba.count: | Count reads in binding sites |
dba.contrast: | Establish contrast(s) for analysis |
dba.analyze: | Execute affinity analysis |
dba.report: | Generate report for a contrast analysis |
dba.plotHeatmap: | Heatmap plot |
dba.plotPCA: | Principal Components plot |
dba.plotBox: | Boxplots |
dba.plotMA: | MA/scatter plot |
dba.plotVenn: | Venn diagram plot |
dba.plotVolcano: | Volcano plot |
dba.show: | Show dba metadata |
dba.mask: | Mask samples or sites |
dba.save: | Save dba object |
dba.load: | Load dba object |
Rory Stark <rory.stark @at@ cruk.cam.ac.uk> and Gord Brown <gdbzork @at@ gmail.com>
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