PSI_Statistic: PSI_Statistic

In EventPointer: An effective identification of alternative splicing events using junction arrays and RNA-Seq data

Description

Statistical analysis of the alternative splicing events. This function takes as input the values of PSI. Perform a statistical analysis based on permutation test

Usage

PSI_Statistic(PSI, Design, Contrast, nboot)

Arguments

PSI	A matrix with the values of the PSI.
Design	The design matrix for the experiment.
Contrast	The contrast matrix for the experiment.
nboot	The number of random analysis.

Value

The output of these functions is a list containing: two data.frame (deltaPSI and Pvalues) with the values of the deltaPSI and the p.values for each contrast, and a third element (LocalFDR) with the information of the local false discovery rate.

Examples

   data(PSIss)
   Design <- matrix(c(1,1,1,1,0,0,1,1),nrow=4)
   Contrast <- matrix(c(0,1),nrow=1)

   # Statistical analysis:

   table <- PSI_Statistic(PSIss$PSI,Design = Design, Contrast = Contrast, nboot = 50)

EventPointer documentation built on Nov. 8, 2020, 7:12 p.m.