This dataset contains HiC data from Seitan et al. 2013. The data was
analysed using HOMER (Heinz et al. 2010) at a resolution of 100kb to
find significant interactions. This example dataset has been filtered
to retain only interactions on chromosomes 14 and 15 with a FDR < 0.1.
The data has also been annotated for overlaps with Refseq promoters.
See the HiC analysis vignette (
more information on how this dataset was created.
A GenomicInteractions object with length 8171.
Seitan, V. C. et al. Cohesin-based chromatin interactions enable regulated gene expression within pre-existing architectural compartments. Genome Res. 23, 2066-77 (2013).
Heinz S, Benner C, Spann N, Bertolino E et al. Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities. Mol Cell 2010 May 28;38(4):576-589.
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