HiLDA: Conducting statistical inference on comparing the mutational exposures of mutational signatures by using hierarchical latent Dirichlet allocation

A package built under the Bayesian framework of applying hierarchical latent Dirichlet allocation to statistically test whether the mutational exposures of mutational signatures (Shiraishi-model signatures) are different between two groups.

Package details

AuthorZhi Yang [aut, cre], Yuichi Shiraishi [ctb]
Bioconductor views Bayesian Sequencing Software SomaticMutation StatisticalMethod
MaintainerZhi Yang <zyang895@gmail.com>
LicenseGPL-3
Version1.4.0
URL https://github.com/USCbiostats/HiLDA https://doi.org/10.1101/577452
Package repositoryView on Bioconductor
Installation Install the latest version of this package by entering the following in R:
if (!requireNamespace("BiocManager", quietly = TRUE))
    install.packages("BiocManager")

BiocManager::install("HiLDA")

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HiLDA documentation built on Nov. 8, 2020, 11:09 p.m.