LRT: Likelihood Ratio Tests for SingleCellAssays

In MAST: Model-based Analysis of Single Cell Transcriptomics

Description

Tests for a change in ET binomial proportion or mean of positive ET Likelihood Ratio Test for SingleCellAssay objects

Usage

LRT(sca, comparison, ...)

## S4 method for signature 'SingleCellAssay,character'
LRT(sca, comparison, referent = NULL, groups = NULL, returnall = FALSE)

Arguments

sca	A SingleCellAssay class object
comparison	A character specifying the factor for comparison
...	ignored
referent	A character specifying the reference level of comparison.
groups	A optional character specifying a variable on which to stratify the test. For each level of groups, there will be a separate likelihood ratio test.
returnall	A logical specifying if additional rows should be returned with information about the different components of the test.

Details

Combined Likelihood ratio test (binomial and normal) for SingleCellAssay and derived objects. This function is deprecated, please use lrTest instead.

Value

data.frame

See Also

zlm ZlmFit

Examples

data(vbetaFA)
LRT(vbetaFA, 'Stim.Condition', 'Unstim')

MAST documentation built on Nov. 8, 2020, 8:19 p.m.