Description Usage Arguments Value See Also Examples
For each base substitution type and transcriptional strand the total number of mutations and the relative contribution within a group is returned.
1 | plot_strand(strand_bias_df, mode = c("relative", "absolute"), colors = NA)
|
strand_bias_df |
data.frame, result from strand_bias function |
mode |
Either "absolute" for absolute number of mutations, or "relative" for relative contribution, default = "relative" |
colors |
Optional color vector for plotting with 6 values |
Barplot
mut_matrix_stranded
,
strand_occurrences
,
plot_strand_bias
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 | ## See the 'mut_matrix_stranded()' example for how we obtained the
## following mutation matrix.
mut_mat_s <- readRDS(system.file("states/mut_mat_s_data.rds",
package = "MutationalPatterns"
))
## Load a reference genome.
ref_genome <- "BSgenome.Hsapiens.UCSC.hg19"
library(ref_genome, character.only = TRUE)
tissue <- c(
"colon", "colon", "colon",
"intestine", "intestine", "intestine",
"liver", "liver", "liver"
)
strand_counts <- strand_occurrences(mut_mat_s, by = tissue)
## Plot the strand in relative mode.
strand_plot <- plot_strand(strand_counts)
## Or absolute mode.
strand_plot <- plot_strand(strand_counts, mode = "absolute")
|
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