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####Using SurvivROC, calculate AU(all)ROC curves.
survivAURC <- function(Stime, status, marker, entry=NULL, cut.values=NULL, time.max=20, by=1) {
#### Replace the 0s with 1s and vice versa since the Heagerty code deals with censored patients opposite to R-CASPAR
#status[status == 0] <- "F"
#status[status == 1] <- 0
#status[status == "F"] <- 1
time.points <- seq(0, time.max, by)
AURC <- 0
AURC_p <- c()
for (t in time.points) {
AURC_t <- survivROC(Stime=Stime, status=status, marker=marker, cut.values=cut.values, predict.time=t, plot=FALSE)
AURC_p <- c(AURC_p, AURC_t$AUC)
}
index <- match("NaN", AURC_p, nomatch=0)
if (length(index) == 1 & index[1] == 0) {
x_axis <- time.points
y_axis <- AURC_p
}
else {
x_axis <- time.points[-index]
y_axis <- AURC_p[-index]
}
AURC <- trapezoid(x_axis, y_axis)
plot(x_axis, y_axis, type="s", xlab=paste("time", "\n", "AUC= ", signif(AURC, 3)), ylab="AUeachROC", main="Area Under ROC curves")
#return(list(AUC=AURC, AUeachROC=AURC_p))
return(list(AUC=AURC, AUeachROC=y_axis))
}
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