RNAinteract-package: Analysis of Pairwise Interaction Screens.

Description Details Package content Author(s) References

Description

The package contains functions to organize the data from (single- and multi-parametric) genetic interaction screens. Methods to estimate main effects (single perturbation effects) and pairwise interactions. p-values are computed. Furthermore a comprehensive html-report is generated.

Details

See vignette("RNAinteract") for details.

Package content

Class RNAinteract (Documentation: RNAinteract-class)

Data input and creating of an object of class RNAinteract.

Data access

Subsetting, summarizing, and binding screens

Main effects and pairwise interactions

Plotting

HTML report

Author(s)

Bernd Fischer

Maintainer: Bernd Fischer <bernd.fischer@embl.de>

References

T. Horn, T. Sandmann, B. Fischer, W. Huber, M. Boutros. Mapping of Signalling Networks through Synthetic Genetic Interaction Analysis by RNAi. Nature Methods, 2011.


RNAinteract documentation built on Nov. 8, 2020, 5:28 p.m.